Zepbound Price 2026: Cost Without Insurance and Where to Get It

Zepbound (tirzepatide) pen
Brand-name tirzepatide by Eli Lilly

Zepbound®

Without insurance, Zepbound costs $299 to $449 a month at Lilly’s self-pay prices for the vial or KwikPen, as long as you refill within 45 days. If your commercial plan covers it, Lilly’s savings card can bring a fill down to $25. Eligible Medicare Part D members pay no more than $50 a month through the Medicare GLP-1 Bridge.
Once-weekly injection FDA-approved Doses 2.5 to 15 mg KwikPen, vial or single-dose pen
Lilly self-pay, vial or KwikPen $299–$449/mo
Commercial plan that covers Zepbound From $25/mo
Medicare Part D (GLP-1 Bridge) Up to $50/mo
List price About $1,087/mo
Prices checked Sep 25, 2026 on LillyDirect, Lilly’s savings page and TrumpRx.gov

What Zepbound is Approved for:

  • Adults with obesity, or with overweight and at least one weight-related medical problem, to lose excess weight and keep it off, along with a reduced-calorie diet and more physical activity
  • Moderate-to-severe obstructive sleep apnea (OSA) in adults with obesity
2.5 mg is a starting dose, not a maintenance dose. Zepbound shouldn’t be used with other tirzepatide or GLP-1 medicines. Mounjaro has the same active ingredient but is approved for type 2 diabetes, not weight loss. Source: zepbound.lilly.com (CMAT-28470 07/2026).
Last Updated:

How Much Does Zepbound Cost? Every Way to Pay

The biggest factor in what you pay for Zepbound is how you pay: cash at Lilly’s self-pay price, a commercial plan with Lilly’s savings card, or Medicare. The table lists each route with the price we found and the date we checked it.
Way to payWhat you payGood to knowChecked
Way to pay
LillyDirect self-pay
VialKwikPen
What you pay
$299–$449 per month
Good to know
2.5 mg $299, 5 mg $399, 7.5 to 15 mg $449 per 28 days if you refill within 45 days. Home delivery or pickup at Walmart Pharmacy. Needles are bought separately.
Checked
Sep 25, 2026
lilly.com
Way to pay
Retail pharmacy with Lilly's self-pay card
KwikPen
What you pay
$299–$449 per month
Good to know
The same prices as LillyDirect for the KwikPen, with or without insurance. Up to 11 fills a year. The card ends December 31, 2026.
Checked
Sep 25, 2026
zepbound.lilly.com
Way to pay
Amazon Pharmacy
KwikPen
What you pay
From $299 starter dose
Good to know
Amazon’s starting price is for the 2.5 mg starter dose. Prime members get free delivery on a first order of a new medication.
Checked
Sep 25, 2026
aboutamazon.com
Way to pay
TrumpRx.gov
Vial
What you pay
From $299 per month
Good to know
Lists Zepbound vials at $299 a month next to a $1,087 list price. Orders are handled by LillyDirect.
Checked
Sep 25, 2026
trumprx.gov
Way to pay
Commercial plan that covers Zepbound
Single-dose pen
What you pay
From $25 per fill
Good to know
With Lilly’s savings card: as little as $25 for a 1-, 2- or 3-month fill. Savings capped at $100 per month of supply and $1,300 a year, up to 13 fills. The card ends December 31, 2026. Your plan may require prior authorization.
Checked
Sep 25, 2026
zepbound.lilly.com
Way to pay
Commercial plan that doesn't cover Zepbound
KwikPenSingle-dose pen
What you pay
$299–$499 per month
Good to know
KwikPen with the self-pay card: $299 to $449. Single-dose pen with the savings card: as low as $499 a month.
Checked
Sep 25, 2026
zepbound.lilly.com
Way to pay
Medicare Part D: GLP-1 Bridge
KwikPen
What you pay
Up to $50 per month
Good to know
For eligible Part D patients with a Zepbound KwikPen prescription for weight management, through December 31, 2027. How the Bridge works.
Checked
Sep 25, 2026
zepbound.lilly.com
Way to pay
List price, no coverage or program
What you pay
About $1,087 per month
Good to know
The monthly price before any Lilly program, as listed on TrumpRx.gov.
Checked
Sep 25, 2026
trumprx.gov

Two habits save the most money. Refill on time: at 10 to 15 mg, a fill costs $449 only if no more than 45 days have passed since the last one, and $699 after that. And check your coverage before you pay cash. A covered plan with the savings card can cost $25 instead of $449.

Telehealth Providers That Prescribe Zepbound

You don’t need a telehealth company to get Zepbound. Your own doctor can prescribe it, and you can fill it at Lilly’s self-pay price. A telehealth provider makes sense if your doctor won’t prescribe it, or if you’d rather do visits and dose check-ins online. These nine providers offer Zepbound, and they sell it in two very different ways. Some send your prescription to LillyDirect and charge a membership on top. Others sell the drug themselves at a flat price of $1,069 to $1,399 a month.

Disclosure: every provider below is an affiliate partner, and we earn a commission if you become a patient through our links. That doesn’t change the order: cards are sorted by estimated monthly total, lowest first. How we make money.
Sesame logo

SesameEst. $358–$548/mo

Checked: Sep 27, 2026

Membership $59–$99/mo
Zepbound (LillyDirect) $299–$449
Medicare Bridge $50/mo copay
Labs included. The membership is billed separately from the drug.
Trustpilot star logo icon used in GLP1Rating reviews
Trustpilot 4.6 (4,5K+)
AgelessRx logo

AgelessRxEst. $364–$514/mo

Read Review

Checked: Sep 25, 2026

Membership $65/mo
Zepbound (LillyDirect vials) $299–$449
Insurance help No
Unlimited messaging and dose adjustments
Found logo

FoundEst. $398–$598/mo

Read Review

Checked: Sep 24, 2026

Branded plan, cash $99–$149/mo
With insurance $49–$89/mo + visits
Medicare Bridge $50/mo copay
Zepbound is billed separately. Our estimate uses Lilly’s self-pay price.
Pallas Health logo

Pallas Health$1,069/mo flat

Checked: Sep 27, 2026

Zepbound $1,069/mo
Membership None
Insurance Cash only
$620 to $770 a month more than Lilly’s self-pay price
No ratings yet
Wellorithm logo

Wellorithm$1,199/mo flat

Checked: Sep 27, 2026

Zepbound $1,199/mo
Membership None
Plan 3 months upfront
Its price note lists a dose that doesn’t exist. Confirm before you pay.
Too few ratings
Eden logo

Eden$1,399/mo

Read Review

Checked: Sep 25, 2026

Zepbound $1,399/mo
Membership (Terms) $39, then $99/mo
Insurance Not stated
FDA warning letter in June 2026; BBB rating F
Wellmedr logo

WellmedrFrom $1,399/mo

Checked: Sep 23, 2026

Zepbound From $1,399/mo
Coaching Included
Insurance No
Its Zepbound page didn’t load on Sep 27. Confirm at checkout.
Trustpilot star logo icon used in GLP1Rating reviews
Trustpilot 4.6 (1,919)
SHED logo

SHEDTotal unclear

Checked: Sep 27, 2026

Membership $99 or $125/mo
Zepbound (LillyDirect) $299–$449
Minimum term 2 months
Its page lists two fees and Lilly prices from before December 2025
Trustpilot star logo icon used in GLP1Rating reviews
Trustpilot 4.6 (1K+)
Sprout Health logo

Sprout HealthPrice not published

Checked: Sep 27, 2026

Price After the quiz
Plans 1, 3 or 6 months
Insurance No
Not available in AL, AR, LA, MS or ND. Full refund before a provider reviews your intake
Trustpilot star logo icon used in GLP1Rating reviews
Trustpilot 4.1 (200+)
Estimated totals add the provider’s fee to the Zepbound price for the doses shown. They leave out needles, lab tests, taxes and shipping unless a card says otherwise. Prices change often, so confirm the total before you pay. Stars show our editorial score for providers we’ve reviewed; other ratings come from Trustpilot.

How to Get Zepbound for the Lowest Legal Price

Check your coverage first. If your commercial plan covers Zepbound, Lilly’s savings card can bring a fill down to $25.

Refill within 45 days. A late refill at 10 mg or more costs $699 instead of $449.

On Medicare Part D? Ask about the Medicare GLP-1 Bridge. Eligible patients pay up to $50 a month for the KwikPen.

Add a telehealth provider only if you need a prescriber. Compare its fee plus the drug price, not the headline price.

Paying cash? Use Lilly’s self-pay price for the vial or KwikPen: $299 to $449 a month through LillyDirect, a retail pharmacy with the self-pay card, or Amazon Pharmacy.

Be wary of anything sold as “generic Zepbound.” There is no FDA-approved generic, and compounded tirzepatide is not FDA-approved.

What Is Zepbound?

Zepbound is Eli Lilly’s brand of tirzepatide, a once-weekly injection. It acts on two gut hormone receptors, GIP and GLP-1, which lowers appetite and slows digestion. The FDA approved it for adults with obesity, or with overweight and at least one weight-related health problem, to lose weight and keep it off along with diet and exercise. It’s also approved for moderate-to-severe obstructive sleep apnea in adults with obesity.

Treatment starts at 2.5 mg a week for four weeks, then 5 mg. The dose can rise in 2.5 mg steps, at least four weeks apart, up to 15 mg. Maintenance doses are 5, 10 or 15 mg. The most common side effects are nausea, diarrhea, vomiting and constipation. Our GLP-1 side effects guide covers what to expect and when to call a doctor.

Mounjaro contains the same drug, tirzepatide, but it’s approved for type 2 diabetes, not weight loss. This page covers Zepbound only. If you’re weighing brand-name Zepbound against a compounded version, read FDA-approved vs. compounded GLP-1s first.

Zepbound single-dose pen, KwikPen and vial beside a doctor reviewing a treatment plan with a smiling patient
Common Questions

Zepbound FAQ

At Lilly’s self-pay prices, a 28-day supply costs $299 for 2.5 mg, $399 for 5 mg and $449 for 7.5 to 15 mg, for the vial or the KwikPen. Those prices hold when you refill within 45 days. The list price is about $1,087 a month.

About $5,087 to $5,637 at Lilly’s self-pay prices, for 13 fills of 28 days. The lower figure is for someone who stays on 5 mg. The higher one follows the label’s dose steps up to 10 to 15 mg. One late refill at 10 mg or more adds $250. See the full cost breakdown.

No. Since the KwikPen launched in February 2026, Lilly charges the same self-pay price for both: $299 to $449 a month. The $299 price doesn’t apply to the single-dose pen.

Lilly’s self-pay prices assume you refill within 45 days. After that, 7.5 mg costs $499, and 10 to 15 mg cost $699 instead of $449.

Through the Medicare GLP-1 Bridge, eligible Part D patients pay no more than $50 a month for Zepbound KwikPen prescribed for weight management. The Bridge runs through December 31, 2027. Who qualifies for the Bridge.

Yes. You need a prescription from a licensed clinician, either your own doctor or a telehealth provider. You then fill it through LillyDirect, a retail pharmacy or Amazon Pharmacy. Telehealth companies charge their own fee on top of the drug, so compare the total.

Some sell the brand-name drug themselves, close to its list price. Others write the prescription and let you buy the drug at Lilly’s self-pay price, then charge a separate membership. Ask which one you’re paying for before you sign up.

It has the same active ingredient, but compounded tirzepatide is not FDA-approved, and the FDA doesn’t review compounded drugs for safety, effectiveness or quality before they’re sold. The rules for compounded GLP-1s are tightening in 2026. What’s changing for compounded GLP-1s.

Often, yes. LillyDirect lists Zepbound as HSA/FSA eligible and notes that eligibility may vary by plan.

Looking More GLP-1 Medications?

How We Checked These Prices

We read Lilly’s LillyDirect and savings pages, TrumpRx.gov and Amazon’s announcement on September 25, 2026, and each provider’s own pricing pages between September 23 and 28, 2026. We don’t buy the drug or sign up for plans. Every number comes from a published page, and each card and table row shows when we checked it. We recheck prices every month. If a price has changed, tell us.

Every provider on this page is an affiliate partner, and we earn a commission when you sign up through our links. Commissions never change the order or what we write. How we make money and our editorial policy explain the rules we follow. We drafted this page with AI assistance and checked every number against its source.

Medical Disclaimer: GLP1Rating provides information for educational purposes and does not give medical advice. GLP-1 medications require a prescription. Talk to a licensed healthcare provider before you start, stop, or change any treatment.
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