SkinnyRx Review 2026: GLP-1 Injections From $99 First Month

SkinnyRx by the Numbers:

The Company Behind SkinnyRx

SkinnyRx is run by Lean Rx, Inc., a Sacramento company founded in 2019. It sells compounded semaglutide and tirzepatide to people paying cash, so there’s no insurance paperwork and no lab requirement. You fill out an online health form and a provider licensed in your state reviews it, usually within 24 hours. Some states also require a short video visit.

Both drugs come as a weekly injection or a daily tablet, and there are microdose plans. State-licensed 503A compounding pharmacies fill the orders. Shipping is free and overnight, and you get tracking within two business days. SkinnyRx also lists the Wegovy pill and Foundayo through a separate membership, but both were unavailable when we checked in September 2026.

Note: Compounded semaglutide and tirzepatide from SkinnyRx are not FDA-approved finished drug products. They are prepared by state-licensed compounding pharmacies under Section 503A of the Federal Food, Drug, and Cosmetic Act.

SkinnyRx Contact Info

Is SkinnyRx Legit? Probation, an FDA Letter and More

• ! LegitScript: probationary certification. LegitScript lists skinnyrx.com as Probationary Certified (checked Oct 20, 2026). It meets their standards, but LegitScript monitors it more closely than a fully certified site.
• ✓ Licensed clinicians. Prescriptions come from clinicians licensed in your state.
• ! 503A pharmacy, not named. State-licensed 503A compounding pharmacies fill the orders, but SkinnyRx doesn’t name them on its site.
• ! Compounded drugs are not FDA-approved. The FDA doesn’t review compounded semaglutide or tirzepatide for safety or effectiveness. What that means for you

Most of the 165 BBB complaints are about one of two things: renewal charges people didn’t expect, or oral tablets that didn’t seem to work. You can avoid the first by reading the renewal terms (see How to cancel SkinnyRx). The second isn’t a SkinnyRx problem as such. Compounded oral semaglutide is absorbed less well than the injection, whoever sells it.

The FDA’s warning letter of February 20, 2026 was about marketing, not a recall. The FDA said product images put the SkinnyRx name on labels as if the company made the drugs, and that the site made unsupported claims about oral and under-the-tongue GLP-1s.

SkinnyRx Cost After the $99 First Month

SkinnyRx publishes first-month prices only: $99 for injectable semaglutide or tirzepatide (a limited-time offer), $149 for semaglutide tablets and $199 for tirzepatide tablets. The price for later months appears at checkout, so confirm it before you pay. No insurance is accepted; FSA/HSA cards and Affirm financing are.

Not in SkinnyRx’s Price

• Lab work (if your provider requests it, you pay separately)
• Anti-nausea or GI support medications
• Insurance reimbursement — SkinnyRx is cash-pay only

SkinnyRx Against the Market Median

A $99 first month for injectable semaglutide or tirzepatide is among the lowest entry prices we’ve seen. For comparison, brand-name Wegovy costs $199 a month for the first two months through NovoCare and $349 after that, and Zepbound costs $299 to $449 a month through LillyDirect. Because SkinnyRx doesn’t publish its month-two price, compare the full cost at checkout before you commit.

Bundles, Renewals and the Early Charge

Bundled subscriptions are non-refundable, and renewals can be charged up to five days before a new period starts. To stop, cancel at least five days before your renewal date. Refunds are available only before a provider completes your prescription review.

How a SkinnyRx Order Actually Happens

Most patients going through this SkinnyRx review process get their first delivery within 3–7 days of completing the quiz.

Read Before You Order SkinnyRx

• 1 Ask for the month-two price. The site only lists first-month prices. You see the full price at checkout.
• 2 Write down your renewal date. Plans renew on their own and can bill up to 5 days early.
• 3 Check your state. Compounded medications aren’t available in Alabama, Louisiana or Mississippi.
• 4 Start with the injection. It has the most evidence behind it. Compounded oral GLP-1s have far less.
• 5 Skip bundles unless you’re sure. Multi-month bundles are non-refundable.

How to Stop SkinnyRx Before It Renews

SkinnyRx plans keep renewing until you cancel, and the charge can go through up to five days before your next period starts. To stop without a surprise charge:

1. Find your next billing date in the SkinnyRx app, under My Plans, then View details.
2. Cancel at least five days before that date. Your plan stays active until the end of the current period.
3. Can’t find the option in the app? Ask support in the in-app chat, at support@skinnyrx.com or at 1-888-979-9580 (Monday to Friday, 9 a.m. to 6 p.m. ET).
4. Keep the confirmation email or a screenshot until the next billing date has passed.

Just need a break? The app lets you push your next refill back by up to two weeks, once per refill period. Refunds are only possible before a provider finishes reviewing your prescription, and bundles aren’t refundable.

Shots, Tablets or Microdoses at SkinnyRx

SkinnyRx offers two active ingredients, semaglutide and tirzepatide, as weekly injections or daily tablets. Many compounded GLP-1 platforms only offer injections.

Important: Compounded tirzepatide tablets are not FDA-approved and are not equivalent to brand-name Zepbound. The FDA has updated compounding regulations following the resolution of tirzepatide shortages in late 2024. In April 2026 the FDA also proposed ending large-scale (503B) compounding of semaglutide and tirzepatide; no final rule had been published as of September 2026. Consult your provider about current legal status in your state.

Members on the injectable report real weight loss. Across Reddit, Trustpilot, and SkinnyRx’s own member data, 22–45 lbs in the first 6–12 months comes up repeatedly. One r/Semaglutide user reported 60 lbs in a year. That tracks with clinical data — Wegovy uses the same active ingredient and showed 15–17% body weight reduction in trials.

Oral formats are a different story. Some users report no effect at all. Compounded oral semaglutide doesn’t include SNAC — the absorption enhancer used in FDA-approved Rybelsus — so how much actually gets absorbed is unpredictable. SkinnyRx recommends the injectable for a reason.

SkinnyRx Highs and Lows

SkinnyRx Reviews: What Patients Post

We checked every public review site that lists SkinnyRx on October 17, 2026. Scores are shown as each site publishes them, with a link. We don’t copy those reviews or mix their scores into the patient reviews on this page.

The pattern is worth knowing. Sites where SkinnyRx asks customers for a review (Trustpilot, the App Store) are very positive. Sites people go to when something went wrong (BBB, ConsumerAffairs) are not. Both can be true: most orders go fine, and the ones that don’t tend to involve refunds, renewals or the oral tablets.

5K+ Trustpilot Reviews of SkinnyRx, in Short

5,452 Trustpilot reviews is a lot. Most GLP-1 telehealth companies have a few hundred. That many reviews is hard to fake. Keep in mind, though, that SkinnyRx asks its customers to leave one, and invited reviews tend to skew positive.

What Redditors Say About SkinnyRx

We read SkinnyRx discussions in r/Ozempic, r/Semaglutide, r/CompoundedSemaglutide and r/GLP1microdosing, plus its Trustpilot and App Store reviews. These themes came up most.

Praise for SkinnyRx

“Injectable semaglutide works just like any other GLP-1 — the mechanism is real. My only issue is cost but $199 is fair.”
— r/Semaglutide

“22 lbs down after 3 months on the injectable. Appetite is basically gone. No major side effects.”
— Trustpilot verified review

Gripes About SkinnyRx

The complaints we saw most often: oral tablets that didn’t seem to work, confusion about billing and subscriptions, and slow customer service. The tablet complaints aren’t really SkinnyRx-specific — compounded oral semaglutide without SNAC is a known absorption problem across the industry. If you’re worried about that, pick the injectable.

Billing complaints mostly come from people who didn’t read the subscription terms. Multi-month plans auto-renew. Once medication ships, you’re not getting a refund. That’s standard in compounded pharmacy — but it still catches people off guard.

Patient reviews of SkinnyRx

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SkinnyRx Next to Its Competitors

See how SkinnyRx compares with five other providers we’ve reviewed on price, brand-name access, insurance, BBB grades and FDA letters in the side-by-side comparison below.

Compare SkinnyRx With Others

Bottom Line

SkinnyRx is one of the cheapest ways to start a GLP-1: $99 for the first month of injections, a prescription usually within a day and free overnight shipping. Its 5,452 Trustpilot reviews at 4.7/5 are the largest review base among the providers we’ve reviewed. It scores 3.6 rather than higher because later-month prices aren’t published, its LegitScript certification is probationary, the FDA sent it a warning letter in February 2026, and the BBB rates it B- with 165 complaints.

If you choose it, start with the injection, check the month-two price at checkout before you pay, and cancel at least five days before a renewal if you change your mind. If you want your full monthly cost up front or need insurance billing, compare the alternatives below first.

Review Update History

• Oct 20, 2026: Rebuilt the review. Under our new five-criteria scoring method, the score moved from 4.9 to 3.6, including a half-point safety deduction for its probationary LegitScript status. Added how to cancel, a checklist for before you sign up, and company contact details.
• Oct 17, 2026: Rechecked prices and review counts on Trustpilot (5,452), Google, the App Store, BBB and ConsumerAffairs.
• Sep 24, 2026: Checked prices, policies and the FDA warning letter.
• May 23, 2026: First published.

All corrections and updates →